{"id":3956,"date":"2020-04-09T15:39:50","date_gmt":"2020-04-09T13:39:50","guid":{"rendered":"https:\/\/www.hertoghe.eu\/?p=3956"},"modified":"2023-10-10T15:47:01","modified_gmt":"2023-10-10T13:47:01","slug":"the-article-of-the-month-of-april-chloroquine-quesaco-dr-poutet","status":"publish","type":"post","link":"https:\/\/www.hertoghe.eu\/en\/the-article-of-the-month-of-april-chloroquine-quesaco-dr-poutet\/","title":{"rendered":"The Article of the Month of April &#8211; &#8220;Chloroquine, Quesaco?&#8221; &#8211; Dr. Poutet"},"content":{"rendered":"<p><a href=\"https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-3953\" src=\"https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois.jpg\" alt=\"\" width=\"307\" height=\"307\" srcset=\"https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois.jpg 2504w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-300x300.jpg 300w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-1024x1024.jpg 1024w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-150x150.jpg 150w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-768x768.jpg 768w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-1536x1536.jpg 1536w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-2048x2048.jpg 2048w, https:\/\/www.hertoghe.eu\/wp-content\/uploads\/Poutet_Avis-du-mois-45x45.jpg 45w\" sizes=\"auto, (max-width: 307px) 100vw, 307px\" \/><\/a>Who hasn&#8217;t heard of chloroquine and Professor Raoult yet? Chloroquine is a molecule, as old as the world (I\u2019m exaggerating just a little bit), known to all frequent travelers in the world, patients with lupus or rheumatoid arthritis\u2026<\/p>\n<p>A controversial comeback of chloroquine?<\/p>\n<p>Professor Raoult, infectiologist and world-renowned specialist in emerging tropical infectious diseases, assures that a treatment with hydroxychloroquine + Azithromycin would make the viral load disappear within a few days in patients who are positive for Covid-19. It reduces the risk of deterioration of the general condition of the patient, provided that this treatment is started at an early stage, as soon as the first symptoms appear.<\/p>\n<p>The controversy comes from the fact that Professor Raoult&#8217;s &#8220;studies&#8221; (1st study carried out on 24 patients, the last on 80 (27\/03\/2020)) present a certain number of biases:<\/p>\n<ul>\n<li>the low number of patients<\/li>\n<li>the absence of a group of patients taking a placebo, principle of a double-blind study *<\/li>\n<li>\u2026<\/li>\n<\/ul>\n<p>There is also the open letter from Dr. Zev Zelenko who practices in the state of New York. He claims that after treating 500 patients based on hydroxychloroquine + Azithromycin + zinc sulfate (zinc slowing viral replication in the cell, hydroxychloroquine helps it to penetrate) there are no deaths, no hospitalizations, no intubation and that only 10% of patients would have transient side effects (nausea, diarrhea). This treatment requires medical monitoring and can in no case be taken in self-medication, more information here.<\/p>\n<p>Geneticist Axel Khan estimates that Professor Raoult&#8217;s results are similar to known data showing 600,000 cases that have progressed in the same way, without treatment!<\/p>\n<p>Others rely on the existence of 2 Chinese studies which show that 10 days after the onset of symptoms in patients with moderate disease, 90% have a controlled viral load, which would not seem to show a major effect of hydroxychloroquine on viral load.<\/p>\n<p>It is clear that at all times in medicine, as elsewhere, such &#8220;controversies&#8221; have taken place! These allow medicine to move forward and in this climate of urgency, the debate will make it possible to find a solution faster for patients.<\/p>\n<p>It seems to me essential that access to hydroxychloroquine and azithromycin remains reserved for primary care physicians (as is the case today in most of our hospitals).<\/p>\n<p>Extensive European research (Discovery, cohort of 3,200 patients) has been underway since March 22<sup>nd<\/sup>. This clinical trial provides 5 modes of treatment given to patients by lot, including hydroxychloroquine. Hopefully the results of this test will come to us soon.<\/p>\n<p>In the meantime, let&#8217;s not play the sorcerer&#8217;s apprentice with our Plaquenil supplies. Hydroxychloroquine looks promising, but let the specialists work with all the means necessary to combat this terrible scourge.<\/p>\n<p>Take care of yourself and your loved ones. Stay home.<\/p>\n<p>&nbsp;<\/p>\n<p>* A double-blind study is a way of verifying the effectiveness of a treatment or a substance, in which one or more groups of well-established subjects receive treatment on an experimental basis, without these subjects or the investigators themselves are not aware of the treatment received, to remove any a priori judgment.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Who hasn&#8217;t heard of chloroquine and Professor Raoult yet? Chloroquine is a molecule, as old as the world (I\u2019m exaggerating just a little bit), known to all frequent travelers in the world, patients with lupus or rheumatoid arthritis\u2026 A controversial comeback of chloroquine? Professor Raoult, infectiologist and world-renowned specialist in emerging tropical infectious diseases, assures [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"cybocfi_hide_featured_image":"","footnotes":""},"categories":[99],"tags":[],"class_list":["post-3956","post","type-post","status-publish","format-standard","hentry","category-healthy-tips"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/posts\/3956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/comments?post=3956"}],"version-history":[{"count":3,"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/posts\/3956\/revisions"}],"predecessor-version":[{"id":4629,"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/posts\/3956\/revisions\/4629"}],"wp:attachment":[{"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/media?parent=3956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/categories?post=3956"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hertoghe.eu\/en\/wp-json\/wp\/v2\/tags?post=3956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}